曹文薰 女 博士

電子郵箱：996838@hainanu.edu.cn

1.教育背景

2013.09-2017.06  沈陽藥科大學  藥物制劑  學士

2017.09-2018.06  西南交通大學  藥學  碩博連讀

2018.09-2024.06  西南交通大學  材料科學與工程  博士

2.科研情況

主要從事有機和無機納米生物材料制劑的研究及設計，通過跨學科構建系列智能響應型的微納米載體應用于心血管疾病的診療研究。近五年來在Chemical Engineering Journal、Advanced Functional Materials、ACS Applied Materials & Interfaces、Acta Biomaterialia等國際重要期刊上發表多篇SCI論文，其中第一作者發表的SCI論文4篇。

3.研究領域

通過智能響應型的微納米載體實現心血管疾病的診療研究。

4.代表性成果

（1）Cao WX ^#, Wei W ^#, Qiu B, Liu Y, Xie S, Fang QB, Li XH*. Ultrasound-powered hydrogen peroxide-responsive Janus micromotors for targeted thrombolysis and recurrence inhibition, Chemical Engineering Journal, 2024, 483: 149187. IF=15.1 (一區)

（2）Cao WX, Xie S, Liu Y, Ran P, Zhang ZL, Fang QB, Li, XH*. Shear stress-triggered theranostic nanoparticles for piezoelectric-Fenton photodynamic thrombolysis and endogenous thrombus imaging, Advanced Functional Materials, 2024, 34: 2312866. IF=19 (一區)

（3）Cao WX, Liu Y, Ran P, He J, Xie S, Weng J*, Li XH*. Ultrasound-propelled Janus rod-shaped micromotors for site-specific sonodynamic thrombolysis. ACS Applied Materials & Interfaces, 2021, 13: 58411-58422. IF=9.5 (二區)

（4）Ran P ^#, Cao WX ^#, Zheng H, Xie S, Zhang GY, Liu Y, Li XH*. Intrabacterial nitroreductase-activated imaging and persistently illuminated photodynamic therapy for intracellular infection theranostics, Advanced Functional Materials, 2024, 2402731. IF=19 (一區)

（5）Zhang ZL ^#, Yan H ^#, Cao WX, Xie S, Ran P, Wei K, Li XH*. Ultrasound-chargeable persistent luminescence nanoparticles to generate self-propelled motion and photothermal/NO therapy for synergistic tumor treatment. ACS Nano, 2023, 17: 16089-16106. IF=17.1 (一區)

（6）Xie SZ ^#, Mo CF ^#, Cao WX, Xie S, Li S, Zhang ZL, Li XH*. Bacteria-propelled microtubular motors for efficient penetration and targeting delivery of thrombolytic Agents. Acta Biomaterialia, 2022, 142: 49-59. IF=9.7 (一區)

（7）Xie SZ ^#, Li S ^#, Cao WX, Mo CF, Zhang ZL, Huang K, Li XH*. Bacteria-templated and dual enzyme-powered microcapsule motors to promote thrombus penetration and thrombolytic efficacy. ACS Applied Materials & Interfaces, 2021, 14: 37553-37565. IF=9.5 (二區)

（8）Xie S ^#, Li Y ^#, Cao WX, Peng JW, Huang K, Meng J, Li XH*. Dual-responsive nanogels with cascaded gentamicin release and lysosomal escape to combat intracellular small colony variants for peritonitis and sepsis therapies. Advanced Healthcare Materials, 2024, 2303671. IF=10 (二區)

（9）Ran P, Zheng H, Cao WX, Jia XW, Zhang GY, Liu Y, Li XH*. On-demand changeable theranostic hydrogels and visual imaging-guided antibacterial photodynamic therapy to promote wound healing. ACS Applied Materials & Interfaces, 2021, 14: 49375-49388. IF=9.5 (二區)

（10）He J ^#, Ran P ^#, Cheng MH, Cao WX, Xie S, Zhang GY, Li XH*. Intracellular infection-responsive release of no and peptides for synergistic bacterial eradication. Journal of Controlled Release, 2022, 352: 87-97. IF=10.8 (一區)